CACNG6, ID (CACNG6, Voltage-dependent calcium channel gamma-6 subunit, Neuronal voltage-gated calcium channel gamma-6 subunit) (AP)

Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). Alternative splicing results in multiple transcript variants. Variants in this gene have been associated with aspirin-intolerant asthma.\n\nApplications:\nSuitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\nImmunohistochemistry: 1:10-50\nImmunofluorescence: 1:10-50\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

033136-AP

Size

200ul

Applications

ELISA, IF, IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Alkaline Phosphatase.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Lee, J.S., et al. BMC Med. Genet. 11, 138 (2010) :\nChen, R.S., et al. Cell Biochem. Biophys. 47(2):178-186(2007)\nChu, P.J., et al. Gene 280 (1-2), 37-48 (2001) :\nBurgess, D.L., et al. Genomics 71(3):339-350(2001)

Additional Info

Human

Alternative Names

CACNG6, Voltage-dependent calcium channel gamma-6 subunit, Neuronal voltage-gated calcium channel gamma-6 subunit