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CARD6 (A2) Peptide

CARD6 (A2) Peptide

Cat no: BS1038P

Supplier: Bioworld Technology, Inc.
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Membrane-associated guanylate kinase (MAGUK) family members localize to the plasma membrane and function as molecular scaffolds for the assembly of multi-protein complexes. The MAGUK family includes several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product, such as postsynaptic proteins, GKAPs, the tight junction associated proteins (ZO-1-3) and the caspase-associated recruitment domain (CARD) proteins, CARD 6, CARD 8-12 and CARD 14. CARD 6 is a 311 amino acid protein that associates with microtubules and acts as a selective mediator of NFkB activation. CARD 6 is structurally and functionally related to the superfamily of interferon (IFN)-inducible GTPases, a group that comprises host defense proteins which mediate cell-autonomous immunity. RICK, the receptorinteracting protein (RIP)-like interacting caspase-like apoptosis regulatory protein kinase, interacts with CARD 6 and targets it to aggresomes, regions of the cell where protein aggregates collect.
Catalogue number: BS1038P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q9BX69
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide CARD6 (A2). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: CARD containing inhibitor of Nod1 and Cardiak-induced NF kB activation; Caspase recruitment domain family; member 6; Caspase recruitment domain protein 6
Additional info: This peptide can be used with studies using BS1038 CARD6 (A2) pAb.

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