Home  >  Products  >  Caspase 3 (Caspase-3, CASP 3, CASP3, CASP-3, CPP-32, Apopain, Yama, SCA-1, ASP3, Apoptosis-related Cysteine Peptidase Apopain, Apopain, Cysteine Protease CPP32, SREBP Cleavage Activity 1, Yama, Yama Protein)
Caspase 3 (Caspase-3, CASP 3, CASP3, CASP-3, CPP-32, Apopain, Yama, SCA-1, ASP3, Apoptosis-related Cysteine Peptidase Apopain, Apopain, Cysteine Protease CPP32, SREBP Cleavage Activity 1, Yama, Yama Protein)

Caspase 3 (Caspase-3, CASP 3, CASP3, CASP-3, CPP-32, Apopain, Yama, SCA-1, ASP3, Apoptosis-related Cysteine Peptidase Apopain, Apopain, Cysteine Protease CPP32, SREBP Cleavage Activity 1, Yama, Yama Protein)

Cat no: C2087-01L

Supplier: United States Biological
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Caspase 3 is ubiquitously expressed and like other caspases is synthesized as an inactive (32kD) proenzyme. Upon activation, Caspase 3 is cleaved at Asp28-Ser29 and Asp175-Ser176 thereby generating two subunits of 17kD and 12kD, respectively. Recent studies have implicated that Caspase 3 is associated with the induction of apoptosis. Activation of Caspase 3 occurs in response to variety of apoptotic inducers including Fas mediated apoptosis. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2087-01L
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
P type: Pab
Purity: Purified by Protein A affinity chromatography.
Additional info: Recognizes human Caspase 3. Species sequence homology: Bovine, chicken, canine, guinea pig, hamster, human, monkey, mouse, porcine, rabbit, rat, yeast.

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