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Caspase 5 p10 pAb

Caspase 5 p10 pAb

Cat no: BS5645

Supplier: Bioworld Technology, Inc.
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Caspase-5 (also designated ICErel-III, TY, ICH-3 and caspase-12 in mouse), can cleave its own precursor, an activity that requires the cysteine 245 residue. Frameshift mutations in caspase-5 have been identified in MMP tumors of the endometrium, colon, and stomach, indicating the caspase-5 may be a new target gene in the microsatellite mutator pathway for cancer. The human caspase 5 gene maps to chromosome 11q22.2-q22.3 and encodes a protein whose expression is barely detectable in most tissues except brain, with highest expression levels being found in lung, liver and skeletal muscle.
Catalogue number: BS5645
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P51878
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 341-386 of Human Caspase-5.
Species: Caspase 5 p10 pAb recognizes endogenous levels of total caspase-5 protein and the p10 subunit of mature caspase-5.
Molecular weight: ~ 10, 48 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Caspase-5; CASP-5; ICE(rel)-III; Protease ICH-3; Protease TY; Caspase-5 subunit p10; CASP5; ICH3; Caspase5
Additional info: For research use only, not for use in diagnostic procedure.

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