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Catenin-(alpha)1/2 (P940) pAb

Catenin-(alpha)1/2 (P940) pAb

Cat no: BS1040


Supplier: Bioworld Technology, Inc.
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a-catenins are a group of proteins associated with cadherin cell-cell adhesion molecules and play indispensable roles in the function of the cadherins. a N-catenin is a linker between cadherin adhesion receptors and the Actin cytoskeleton and is essential for stabilizing dendritic spines in rodent hippocampal neurons in culture. A deletion in this protein causes cerebellar and hippocampal lamination defects and impaired startle reaction. a E- and a N-catenin appear to co-localize in cell bodies of neurons in dorsal root ganglia. In mice, a N-catenin was found to occur at the roof plate of the mesencephalon and diencephalon, coinciding with Wnt-1 expression.
Catalogue number: BS1040
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P35221/P26232
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids C-terminus of Human Catenin-(alpha)2.
Species: Catenin-(alpha)1/2 (P940) pAb detects endogenous levels of Catenin-(alpha)1/2 protein.
Molecular weight: ~ 100 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Catenin alpha-1; Alpha E-catenin; Cadherin-associated protein; Renal carcinoma antigen NY-REN-13; CTNNA1; Catenin-(alpha)1; Catenin (alpha)1; (alpha)E-catenin; Catenin alpha-2; Alpha N-catenin; Alpha-catenin-related protein; CTNNA2; CAPR; Catenin-(alpha)2; Catenin (alpha)2; (alpha)N-catenin;
Additional info: For research use only, not for use in diagnostic procedure.

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