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CBP80 (R5) Peptide

CBP80 (R5) Peptide

Cat no: BS2040P

Supplier: Bioworld Technology, Inc.
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In eukaryotes, the majority of mRNAs have an m(7)G cap, which is added cotranscriptionally and plays a critical role in many aspects of mRNA metabolism. The effect of the cap on translation is mediated by the initiation factor eIF-4F, whereas the effect on pre-mRNA splicing involves a nuclear complex(CBC). CBC consists of two cap binding proteins CBP20 and CBP80, which mediate the stimulatory functions of the cap in pre-mRNA splicing, 3' end formation and U snRNA export. The genes CBC1 and CBC2 encode CBP80 and CBP20, respectively. CBP80 comprises three domains, each containing a MIF4G domain. CBP20 has an RNAP fold and associates with the second and third domains of CBP80.
Catalogue number: BS2040P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q09161
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide CBP80 (R5). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Nuclear cap-binding protein subunit 1; 80 kDa nuclear cap-binding protein; CBP80; NCBP 80 kDa subunit; NCBP1; CBP80; NCBP
Additional info: This peptide can be used with studies using BS2040 CBP80 (R5) pAb.

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