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CBX5 mAb

CBX5 mAb

Cat no: MB0063


Supplier: Bioworld Technology, Inc.
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Heterochromatin protein 1 (HP1) is a family of heterochromatic adaptor molecules involved in both gene silencing and higher order chromatin structure. All three HP1 family members ((alpha), (beta), and (gamma)) are primarily associated with centromeric heterochromatin; however, HP1(beta) and (gamma) also localize to euchromatic sites in the genome. HP1 proteins are approximately 25 kDa in size and contain a conserved amino-terminal chromodomain, followed by a variable hinge region and a conserved carboxy-terminal chromoshadow domain. The chromodomain facilitates binding to histone H3 tri-methylated at Lys9, a histone "mark" closely associated with centromeric heterochromatin.
Catalogue number: MB0063
Reactivities: Human, Mouse
Hosts: Mouse
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P45973
Dilutions: WB: 1:1000 ICC: 1:100~500
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human CBX5.
Species: This antibody detects endogenous levels of CBX5 and does not cross-react with related proteins
Molecular weight: Predicted band size:22KDa Observed band size:25KDa
Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha; HP1(alpha); CBX5; HP1A
Additional info: For research use only, not for use in diagnostic procedure.

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