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CCR6 (Chemokine Receptor 6, CC-CCR-6)

Cat no: C2099-70B

CCR6 (Chemokine Receptor 6, CC-CCR-6)

CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. It is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP 3 alpha). This receptor has been shown to be important for B lineage maturation and antigen driven B cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. CCR6 has been reported to be expressed in intestine, colon, liver, lymph node, spleen, lung, blood, umbilical cord, placenta, skin, and pancreas. It has also been reported to be expressed in lymphocytes, T cells, and B cells.\n\nApplications:\nSuitable for use in ELISA, Immunohistochemistry, Western Blot and Flow Cytometry. Other applications not tested.\n\nRecommended Dilutions:\nELISA: 1:37,500\nFlow Cytometry: 2-6ul/10e6 cells in 100ul\nImmunohistochemistry (Paraffin): 1:125\nImmunohistochemistry: 1:10-1:2000\nWestern Blot: 1:250\nOptimal dilutions to be determined by the researcher.\n\nPositive Control:

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SPECIFICATIONS

Catalog Number

C2099-70B

Size

100ug

Applications

ELISA, FC, IHC, IP, WB

Hosts

Goat

Reactivities

Hum, Mouse

Form

Supplied as a liquid in PBS, pH 7.2, 1mg/ml BSA, 0.1% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1. Baba M et al., J Biol Chem 272 14893-8 (1997).

Additional Info

Recognizes human CCR6. Species Crossreactivity: mouse

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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