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CCR9 (C-C chemokine receptor type 9, CC-CKR-9, C-C CKR-9, CCR-9, CDw199, GPR28, GPR-9-6, G-protein coupled receptor 28)

Cat no: C2100-11

CCR9 (C-C chemokine receptor type 9, CC-CKR-9, C-C CKR-9, CCR-9, CDw199, GPR28, GPR-9-6, G-protein coupled receptor 28)

Chemokine receptors are specialized proteins that function at the surface of cells, and enable chemokines to trigger internal cellular processes. Chemokines and their receptors play a pivotal role in lymphocyte trafficking, recruiting and recirculation. Chemokines act through seven transmembrane G protein-coupled receptors. The chemokine system is increasingly recognized to play an important role in lymphocyte biology. \n\nApplication(s):\nELISA: 1:100,000 \nWestern Blotting: 1:1,000 \nImmunohistochemistry: 1:250 \nFlow Cytometry: 1:200 \n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

C2100-11

Size

100ug

Applications

ELISA, FC, IHC, WB

Hosts

Goat

Reactivities

Hum, Mouse

Form

Supplied as a liquid in PBS, pH 7.2, 1mg/ml BSA, 0.1% sodium azide before the addition of 40% glycerol.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

Zaballos,A,. et. al. identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. J. Immunol. 162 (10), 5671-5675 (1999)

Additional Info

Peptide sequence is < 50% identical to other mouse chemokine receptors in this region. Recognizes mouse CCR9 and Crossreacts to human CCR9 with approximately 50% less titer. Crossreacts with mouse and human.

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