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CCT2 (T-complex Protein 1 Subunit beta, TCP-1-beta, CCT-beta, CCTB, 99D8.1)

Cat no: T2035-10L

CCT2 (T-complex Protein 1 Subunit beta, TCP-1-beta, CCT-beta, CCTB, 99D8.1)

TCP-1b (Chaperonin containing T complex polypeptide 1, subunit 2) belongs to the TCP-1 chaperonin family, predicted molecular weight 57kD. Chaperonin-containing TCP-1 is a large multisubunit complex of 800-900kD, a protein complex considered to be the cytosolic homologue of mitochondrial HSP60. TCP-1b has been shown to interact with b-actin, 14-3-3, SUMO4, TCP-1a, b-Tubulin, a-Tubulin and CCT8. In vitro, TCP-1b mediates the ATP-dependent folding of tubulin, actin, and a-transducin. This protein is also essential for cyclin E maturation and accumulation.\n\nApplications:\nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 5-10ug/5ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

T2035-10L

Size

100ug

Applications

WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Mab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG2a,k

References

1. Yaffe MB, et al. 1992. Nature 358:245.

Additional Info

Recognizes TCP-1b. Species Crossreactivity: human, mouse, rat and frog.

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