Home  >  Products  >  CD10 (Neprilysin, Atriopeptidase, Common Acute Lymphocytic Leukemia Antigen, CALLA, Enkephalinase, Neutral Endopeptidase 24.11, NEP, Neutral Endopeptidase, Skin Fibroblast Elastase, SFE, MME, EPN)
CD10 (Neprilysin, Atriopeptidase, Common Acute Lymphocytic Leukemia Antigen, CALLA, Enkephalinase, Neutral Endopeptidase 24.11, NEP, Neutral Endopeptidase, Skin Fibroblast Elastase, SFE, MME, EPN)

CD10 (Neprilysin, Atriopeptidase, Common Acute Lymphocytic Leukemia Antigen, CALLA, Enkephalinase, Neutral Endopeptidase 24.11, NEP, Neutral Endopeptidase, Skin Fibroblast Elastase, SFE, MME, EPN)

Cat no: C2261-48K

Supplier: United States Biological
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CD10 is a 100kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein, also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides. Applications: Suitable for use in Flow Cytometry and Western Blot. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)0.5ug/10e5 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2261-48K
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Knapp, W., 1989. Leucocyte Typing IV. Oxford University Press, New York. 2. Barclay, N., et al. 1997. The Leucocyte Antigen Facts Book. Academic Press Inc. San Diego. 3. Schlossman, S., et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York. 4. Denny, M.F., et al. 2010. J. Immunol. 184:3284. 5. Yoshino, N., et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC) 6. Shipp, M., et al. 1993. Blood 82:1052. 7. Lu, B., et al. 1995. J. Exp. Med. 181:2271.
Additional info: Recognizes human CD10. Species Crossreactivity: chimpanzee, baboon, cynomolgus, rhesus.

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