Home  >  Products  >  CD106 (CD106 Antigen, DKFZp779G2333, INCAM 100, INCAM-100, L1CAM, MGC99561, Vascular Cell Adhesion Molecule 1, VCAM 1, VCAM1, VCAM-1, Vascular Cell Adhesion Protein 1)

CD106 (CD106 Antigen, DKFZp779G2333, INCAM 100, INCAM-100, L1CAM, MGC99561, Vascular Cell Adhesion Molecule 1, VCAM 1, VCAM1, VCAM-1, Vascular Cell Adhesion Protein 1)

Cat no: C2446-75J


Supplier: United States Biological
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VCAM-1, which is present on activated endothelial cells. VCAM-1 is an adhesion molecule, which binds to the integrin alpha4/beta1 (VLA-4) and to the integrin alpha4/beta7 on lymphocytes. This antibody has been shown to inhibit T lymphocyte adhesion to TNF stimulated endothelial cells. The molecular weight of the recognized antigen is 110kD. Applications: Suitable for use in Immunohistochemistry, Adhesion studies and Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: NS1 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2446-75J
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry
Size: 200ug
Form: Supplied as a lyophilized powder in PBS, 1mg/ml BSA. Reconstitute with 1ml sterile dH2O.
P type: Mab
Isotype: IgG1
Purity: Purified
References: 1. Thornhill, M., et al., (1991), "TNF combines with IL-4 or IFN-y to selectively enhance endothelial cell adhesiveness for T cells: the contribution of VCAM-1 dependent and independent binding mechanisms", J. Immunol. 146: 592. 2. This antibody has been assigned at the Vth International Workshop on Human Leucocyte Differentiation Antigens in Boston (1993). Identification number: E039.
Additional info: Recognizes VCAM-1.

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