Home  >  Products  >  CD106 (CD106 Antigen, DKFZp779G2333, INCAM 100, INCAM-100, L1CAM, MGC99561, Vascular Cell Adhesion Molecule 1, VCAM 1, VCAM1, VCAM-1, Vascular Cell Adhesion Protein 1)
CD106 (CD106 Antigen, DKFZp779G2333, INCAM 100, INCAM-100, L1CAM, MGC99561, Vascular Cell Adhesion Molecule 1, VCAM 1, VCAM1, VCAM-1, Vascular Cell Adhesion Protein 1)

CD106 (CD106 Antigen, DKFZp779G2333, INCAM 100, INCAM-100, L1CAM, MGC99561, Vascular Cell Adhesion Molecule 1, VCAM 1, VCAM1, VCAM-1, Vascular Cell Adhesion Protein 1)

Cat no: C2447-02J

Supplier: United States Biological
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Vascular adhesion molecule 1 (VCAM-1) is a cell surface glycoprotein that is also known as CD106. CD106 is expressed predominantly on endothelial cells and expression is up-regulated during inflammation. The ligand for CD106 is the alpha 4 subunit (CD49d) of the integrin VLA-4 (CD49d/CD29). Applications: Suitable for use in Flow Cytometry and Immunohistochemistry . Other applications not tested. Recommended Dilution: Flow Cytometry: 1:10-1:50; 10ul labels 10e6 cells in 100ul Immunohistochemistry: frozen sections Optimal dilutions to be determined by the researcher. Hybridoma: PX63-Ag8.653 myeloma cells with spleen cells from Lewis rats. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2447-02J
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry, Immunohistochemistry
Size: 250ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
P type: Mab
Isotype: IgG2a
Purity: Purified by Protein G affinity chromatography.
References: 1. Kinashi, T. and Springer, T.A. (1994) 20:25-44. 2. Wormley, F.L. et al. (2001) Infect. Immun. 69:5072-5079. 3. Woo, J.M. et al. (2010) Arthritis Res Ther. 12(3):R93. 4. Hall, L.J. et al. (2010) P J Immune Based Ther Vaccines. 8: 5. 5. Winnik, S. et al. (2011) Eur Heart J. Feb 9. [Epub ahead of print] 6. Hamada, T. et al. (2009) Am J Pathol. 174: 2265-77. 7. Hamada, T. et al. (2008) Hepatology. 47: 186-98. 8. Baumer, Y. et al. (2011) Exp Biol Med (Maywood). 236: 692-700. 9. Lau,. H.Y. and Bhatia, M. (2007) Am J Physiol Gastrointest Liver Physiol. 292: G1283-92.
Additional info: Recognizes mouse VCAM-1. Reported to partially block VCAM-1 mediated functions (ref1).

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