CD106 (CD106 Antigen, INCAM 100, INCAM-100, L1CAM, Vascular Cell Adhesion Molecule 1, V-CAM 1, VCAM1, VCAM-1, Vascular Cell Adhesion Protein 1)

Human CD106 is an endothelial adhesion molecule that binds to 41 & 47 integrins (VLA-4) and promotes adhesion of lymphocytes, monocytes, eosinophils and basophils. CD106 is also found on follicular dendritic cells, interdigitating recticulum cells and Kupffer cells. \n\nApplications:\nSuitable for use in ELISA, Western Blot, Flow Cytometry and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C2446-71FX

Size

100ug

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in 50mM sodium phosphate, pH 7.5, 100mM potassium chloride, 50mM sodium chloride. No preservative added.

P Type

Mab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG1

References

1. M.H. Thornhill, D.O. Haskard, (1991) J Immunol 146: 592-598, 2. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1764-1767, 3. M. Nagata, et al, (1995) J Immunol 155: 2194-2202, 4. H.E. Chuluyan, et al, (1995) J Immunol 155: 3135-3144, 5. K.D. Patel (1998) Blood 92 (10): 3904-3911, 6. S.R. Barthel, M.W. Johansson, et al. (2006) J Biol Chem281(43): 32175-32187.

Additional Info

Recognizes the human VCAM-1 molecule, CD106, and blocks leukocyte adhesion.

Alternative Names

DKFZp779G2333, MGC99561