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Products CD117 (c-kit, Stem Cell Factor, SCF Receptor, Steel Factor Receptor, Mast Cell Growth Factor, MGF)
| Catalogue number: | C2448-04Q |
| Reactivities: | Human |
| Hosts: | Rabbit |
| Applications: | Immunohistochemistry |
| Size: | 500ul |
| Form: | PBS pH7.3 |
| P type: | Pab |
| Isotype: | IgG |
| Purity: | Purified |
| Alternative names: | CD117 antigen, C-Kit, Mast/stem cell growth factor receptor precursor, PBT, Proto-oncogene tyrosine-protein kinase Kit, SCFR, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| References: | This product has been used in:Arber DA et al. Paraffin section detection of the c-kit gene product (CD117) in human tissues: value in the diagnosis of mast cell disorders. Hum Pathol 29:498-504 (1998). |
| Additional info: | This antibody recognizes a protein of 145kD identified as CD117/p145kit. In normal cells, the CD117 antibody has been shown to label breast epithelium, germ cells, melanocytes, stem cells and mast cells. In abnormal cells, it has been shown to label testicular germ cells, endometrial carcinomas, papillary and follicular thyroid carcinomas, small cell carcinomas, melanomas and ovarian epithelial carcinomas. It has also been shown to be an effective marker for mast cell disorders, gastrointestinal stromal tumors and immunotyping of blasts in human bone marrow. Species Crossreactivity: Crossreacts with Human. |
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