Home  >  Products  >  CD11a (CD11 Antigen-like Family Member A, Integrin alpha-L, ITGAL, Leukocyte Adhesion Glycoprotein LFA-1 alpha Chain, Leukocyte Function-associated Molecule 1 alpha Chain, LFA1A, LFA-1A, LFA-1)
CD11a (CD11 Antigen-like Family Member A, Integrin alpha-L, ITGAL, Leukocyte Adhesion Glycoprotein LFA-1 alpha Chain, Leukocyte Function-associated Molecule 1 alpha Chain, LFA1A, LFA-1A, LFA-1)

CD11a (CD11 Antigen-like Family Member A, Integrin alpha-L, ITGAL, Leukocyte Adhesion Glycoprotein LFA-1 alpha Chain, Leukocyte Function-associated Molecule 1 alpha Chain, LFA1A, LFA-1A, LFA-1)

Cat no: C2262-02R

Supplier: United States Biological
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CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages with increase in levels on memory T cells. CD11a or LFA 1 has a key role in mediating leukocyte adhesion to endothelium during inflammatory responses through binding to ICAM 1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many T cell functions and immune phenomena. Mol. weight in SDS gels is about 180kD. Part of heterodimer with CD18 (integrin b2). A defect in b-2 expression results in leukocytes adhesion deficiency (LAD) in which patients suffer from recurring bacterial infections. Applications: Suitable for use in Immunofluorescence, Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: frozen Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with 1ml ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2262-02R
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry
Size: 1ml
Form: Supplied as a lyophilized powder in sodium azide. Reconstitute with 1ml ddH2O.
P type: Mab
Isotype: IgG1
Purity: Purified
Alternative names: Integrin alpha L (Antigen CD11A (p180), Lymphocyte Function-associated Antigen 1; alpha Polypeptide)
Additional info: Recognizes human CD11a.

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