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CD11a (Integrin Alpha L, ITGAL, Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain, LFA1A, Ly15, Ly21, Lymphocyte Function Associated Antigen Type 1 alpha, p180)

CD11a (Integrin Alpha L, ITGAL, Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain, LFA1A, Ly15, Ly21, Lymphocyte Function Associated Antigen Type 1 alpha, p180)

Cat no: C2262-02H1

Supplier: United States Biological
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CD11a is a member of the integrin family of cell adhesion molecules. It is a glycoprotein expressed in combination with the CD18 beta chain. The complex is a member of the beta 2 integrin family. These molecules function in cell adhesion and specifically bind to CD54, ICAM2, ICAM3. CD11a is expressed on thymocytes, T and B lymphocytes, granulocytes, monocytes, and macrophages. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2262-02H1
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100ug
Form: In PBS with 15mM Sodium Azide. pH 7.4
P type: Mab
Isotype: IgG1
Purity: Purified by immunoaffinity chromatography.
Alternative names: Integrin Alpha L, ITGAL, Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain, LFA1A, Ly15, Ly21, Lymphocyte Function Associated Antigen Type 1 alpha, p180
References: 1. Landis RC et al. Involvement of the I domain of LFA-1 in selective binding to ligands ICAM-1 and ICAM-3. J Cell Biol 126:529-37 (1994). 2. Landis RC et al. A novel LFA-1 activation epitope maps to the I domain. J Cell Biol 120:1519-27 (1993). 3. Knapp W et al. (eds.) Leucocyte typing IV. Oxford University Press (1989).
Additional info: The antibody recognizes an unique epitope on CD11a antigen (LFA-1 alpha chain) implicated in activation of LFA-1 complex. Species Crossreactivity: Crossreacts with Human.

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