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Products CD11a (Integrin Alpha L, ITGAL, Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain, LFA1A, Ly15, Ly21, Lymphocyte Function Associated Antigen Type 1 alpha, p180)
| Catalogue number: | C2262-06U |
| Reactivities: | Mouse |
| Hosts: | Rat |
| Applications: | Flow Cytometry, Immunoprecipitation |
| Size: | 500ug |
| Form: | Supplied as a liquid in PBS, pH 7.4. No preservative added. |
| P type: | Mab |
| Isotype: | IgG2a |
| Purity: | Purified by Protein G affinity chromatography. |
| Alternative names: | Integrin Alpha L, ITGAL, Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain, LFA1A, Ly15, Ly21, Lymphocyte Function Associated Antigen Type 1 alpha, p180 |
| References: | 1. Trowbridge, I.S. and Omary, M.B. (1981) Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen MAC-1. J. Exp. Med. 154:1517-1524 2. Champe, M. et al. (1995) Monoclonal Antibodies That Block the Activity of Leukocyte Function-associated Antigen-1 Recognize Three Discrete Epitopes in the Inserted Domain of CD11a. J. Biol. Chem. 270:1388-1394 3. Springer, T. et al. (1982) LFA-1 and Lyt-2,3, molecules associated with T lymphocyte-mediated killing; and Mac-1, an LFA-1 homologue associated with complement receptor function Immunol. Rev. 68: 171-195. 4. Falanga, P. B. and Butcher E. C. (1991) Late treatment with anti-LFA-1 (CD11a) antibody prevents cerebral malaria in a mouse model. Eur. J. Immunol. 21: 2259-2263. 5. Campbell, S.B. et al. (2001) CD4 ligation promotes the IL-4-independent development of IL-4-producing clones from naive CD4(+) T cells J. Immunol.167:5610-5619 6. Talento, A. et al. (1993) A single administration of LFA-1 antibody confers prolonged allograft survival. Transplantation.55(2): 418-22 7. Barret, T.B. et al. (1991) CD40 signaling activates CD11a/CD18 (LFA-1)-mediated adhesion in B cells. J. Immunol. 146(6): 1722-9. |
| Additional info: | Recognizes mouse CD11a. |
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