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Products CD11b (CD11 Antigen-like Family Member B, Cell Surface Glycoprotein MAC-1 Subunit alpha, CR-3 alpha Chain, CR3A, Integrin alpha M, Integrin alpha-M, ITGAM, Leukocyte Adhesion Receptor MO1, Neutrophil Adherence Receptor)
| Catalogue number: | C2262-52M |
| Reactivities: | Rat |
| Hosts: | Mouse |
| Applications: | Immunohistochemistry |
| Size: | 250ug |
| Form: | Suppplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. |
| P type: | Mab |
| Isotype: | IgG1 |
| Purity: | Purified by Protein G affinity chromatography. |
| Alternative names: | Integrin, alpha M (Complement Component 3 Receptor 3 Subunit) |
| References: | 1. Damoiseaux, J.G.M.C. et al. (1989) Heterogeneity of macrophages in the rat evidenced by variability in determinants: two new anti-rat macrophage antibodies against a heterodimer of 160 and 95kD (CD11/CD18). J. Leukoc. Biol. 46: 556-564. 2. De Groot, C.J.A. et al. (1988) Discrimination between different types of neuroglial cells in rat central nervous system using combined immuno- and enzyme-histochemical methods. Immunobiology. 178: 177-190. 3. Dijkstra, C.D. and Damoiseaux, J.G.M.C. (1993) Macrophage heterogeneity established by immunocytochemistry. Prog. Histochem. Cytochem. 27: 1-65. 4. Huitinga, I. et al. (1993) Treatment with anti CR3 antibodies ED7 and ED8 suppresses experimental allergic encephalomyelitis in Lewis rats. Eur. J. Immunol. 23: 709-715. 5. Zilka, N. et al. (2009) Human misfolded truncated tau protein promotes activation of microglia and leukocyte infiltration in the transgenic rat model of tauopathy. J. Neuroimmunol. 209: 16-25. |
| Additional info: | Recognizes a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. It also recognises small ramified microglia in the central nervous system. No other cell types are positive. |
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