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CD11b (CD11 Antigen-like Family Member B, Cell Surface Glycoprotein MAC-1 Subunit alpha, CR-3 alpha Chain, CR3A, Integrin alpha-M, ITGAM, Leukocyte Adhesion Receptor MO1, MAC-1, MAC1A, MGC117044, MO1A, Neutrophil Adherence Receptor, SLEB6)

Cat no: C2262-51H

CD11b (CD11 Antigen-like Family Member B, Cell Surface Glycoprotein MAC-1 Subunit alpha, CR-3 alpha Chain, CR3A, Integrin alpha-M, ITGAM, Leukocyte Adhesion Receptor MO1, MAC-1, MAC1A, MGC117044, MO1A, Neutrophil Adherence Receptor, SLEB6)

CD11b associates with CD18 to form the heterodimeric complex known as Mac-1. This complex serves as a receptor for the iC3b component. Mac-1 also serves as an adhesion molecule for intracellular adhesion molecule-1, also known as CD54. Mac-1 is expressed on cells of the mycloid lineage as well as natural killer cells.\n\nApplications: \nSuitable for use in Immunofluorescence, Immunoprecipitation and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunofluorescence: 1:5-1:10 in PBS.\nImmunohistochemistry (frozen): 1:5-1:10 in PBS. \nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C2262-51H

Size

1ml

Applications

IF, IHC, IP

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.

P Type

Mab

Purity

Purified

Isotype

IgG1

References

1. Keizer, G.D., et al., 1985, Eur. J. Immunol. 15, 1142.

Additional Info

Recognizes human CD11b CR3 alpha chain of the CD11b/CD18 (p165, 95) integrin heterodimer on NK-cells, monocytes and granulocytes.

Alternative Names

Integrin, alpha M (Complement Component 3 Receptor 3 Subunit)

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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