Home  >  Products  >  CD11b (CD11 Antigen-like Family Member B, Cell Surface Glycoprotein MAC-1 Subunit alpha, CR-3 alpha Chain, CR3A, Integrin alpha-M, ITGAM, Leukocyte Adhesion Receptor MO1, MAC-1, MAC1A, MGC117044, MO1A, Neutrophil Adherence Receptor, SLEB6)
CD11b (CD11 Antigen-like Family Member B, Cell Surface Glycoprotein MAC-1 Subunit alpha, CR-3 alpha Chain, CR3A, Integrin alpha-M, ITGAM, Leukocyte Adhesion Receptor MO1, MAC-1, MAC1A, MGC117044, MO1A, Neutrophil Adherence Receptor, SLEB6)

CD11b (CD11 Antigen-like Family Member B, Cell Surface Glycoprotein MAC-1 Subunit alpha, CR-3 alpha Chain, CR3A, Integrin alpha-M, ITGAM, Leukocyte Adhesion Receptor MO1, MAC-1, MAC1A, MGC117044, MO1A, Neutrophil Adherence Receptor, SLEB6)

Cat no: C2262-51H

Supplier: United States Biological
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CD11b associates with CD18 to form the heterodimeric complex known as Mac-1. This complex serves as a receptor for the iC3b component. Mac-1 also serves as an adhesion molecule for intracellular adhesion molecule-1, also known as CD54. Mac-1 is expressed on cells of the mycloid lineage as well as natural killer cells. Applications: Suitable for use in Immunofluorescence, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunofluorescence: 1:5-1:10 in PBS. Immunohistochemistry (frozen): 1:5-1:10 in PBS. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2262-51H
Reactivities: Human
Hosts: Mouse
Applications: Immunofluorescence, Immunohistochemistry, Immunoprecipitation
Size: 1ml
Form: Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified
Alternative names: Integrin, alpha M (Complement Component 3 Receptor 3 Subunit)
References: 1. Keizer, G.D., et al., 1985, Eur. J. Immunol. 15, 1142.
Additional info: Recognizes human CD11b CR3 alpha chain of the CD11b/CD18 (p165, 95) integrin heterodimer on NK-cells, monocytes and granulocytes.

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