Home  >  Products  >  CD11b (CD11 Antigen-like Family Member B, Cell Surface Glycoprotein MAC-1 Subunit alpha, CR-3 alpha Chain, CR3A, Integrin alpha-M, ITGAM, Leukocyte Adhesion Receptor MO1, MAC-1, MAC1A, MGC117044, MO1A, Neutrophil Adherence Receptor, SLEB6) (FITC)
CD11b (CD11 Antigen-like Family Member B, Cell Surface Glycoprotein MAC-1 Subunit alpha, CR-3 alpha Chain, CR3A, Integrin alpha-M, ITGAM, Leukocyte Adhesion Receptor MO1, MAC-1, MAC1A, MGC117044, MO1A, Neutrophil Adherence Receptor, SLEB6) (FITC)

CD11b (CD11 Antigen-like Family Member B, Cell Surface Glycoprotein MAC-1 Subunit alpha, CR-3 alpha Chain, CR3A, Integrin alpha-M, ITGAM, Leukocyte Adhesion Receptor MO1, MAC-1, MAC1A, MGC117044, MO1A, Neutrophil Adherence Receptor, SLEB6) (FITC)

Cat no: C2262-51F

Supplier: United States Biological
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CD11b associates with CD18 to form the heterodimeric complex known as Mac-1. This complex serves as a receptor for the iC3b component. Mac-1 also serves as an adhesion molecule for intracellular adhesion molecule-1, also known as CD54. Mac-1 is expressed on cells of the mycloid lineage as well as natural killer cells. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 5ug labels 1x10e6 cells Excitation 488nm, Peak emission 525nm. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
Catalogue number: C2262-51F
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 500ul
Form: Supplied as a liquid in PBS, BSA, 0.05% sodium azide. Labeled with FITC.
P type: Mab
Isotype: IgG1
Purity: Purified
Alternative names: Integrin, alpha M (Complement Component 3 Receptor 3 Subunit)
References: 1. Rainherz, E.L.., et al, 1986, Leukocyte Typing II. Springer-Verlag Inc., New York Diamond,M.S., .E.Staunton, S.D.Marin and T.A.Springer. 1991, Cell 65: 961. 2. Maurer,D., G.Fisher, O. Majdic, W.Hinterberger and W.Knapp. Ann.Hematol. 62:135. 3. Diamond,M.S., J.Garcia-Aguilar, J.K.Bickford, A.L.Corbl and T.A.Springer. 1993. J.Cell Biol. 120: 1031. 4. Bohuslav,J., V.Horejsi, C.Hansmann, J.Stockl, U.H.Weidle, O.Majdic, I.Bartke, W.Knapp and H.Stockringer. 1995, J.Exp.Med. 181: 1381. 5. Stockl,J., O.Majdic, W.F.Pickl, A.Rosenkranz, E.Prager, E.Gschwantler and W.Knapp. 1995, J.Immunol. 154: 5453. 6. Thornton,B.P., et al. 1996, J.Immunol. 156: 1235.
Additional info: Recognizes human CD11b CR3 alpha chain of the CD11b/CD18 (p165, 95) integrin heterodimer on NK-cells, monocytes and granulocytes.

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