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CD11b (Cell Surface Glycoprotein MAC1 Alpha Subunit, Complement Component Receptor 3 Alpha, CR3A, ITGAM, MAC1A, MO1A, Neutrophil Adherence Receptor)

Cat no: C2262-34Y

CD11b (Cell Surface Glycoprotein MAC1 Alpha Subunit, Complement Component Receptor 3 Alpha, CR3A, ITGAM, MAC1A, MO1A, Neutrophil Adherence Receptor)

CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is also a marker for hematopoietic/neural stem and progenitor cells and microglia.\n\nMutations in the CD11b protein have been assosicated with the autoimmune disease lupus, and CD11b antibodies are therefore commonly in immunology studies.\n\nApplications:\nSuitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Other applications not tested.\n\nRecommended Dilution:\nFlow Cytometry: Neat; 10ul labels 10e6 cells in 100ul\nImmunohistochemistry: frozen\nOptimal dilutions to be determined by the researcher.\n\nRecommended Secondary Antibodies:\nI1904-06C: IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo\nI1904-06H IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo\nI1904-14C: IgG, Fc (HRP) Pab Gt xMo\nI1904-19C: IgG, F(ab

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SPECIFICATIONS

Catalog Number

C2262-34Y

Size

2ml

Applications

FC, IHC, IP

Hosts

Mouse

Reactivities

Bov, Can, Fel, Goat, Prc

Form

Suuplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.

P Type

Mab

Purity

Supernatant

Isotype

IgG1

References

1. Danilenko, D.M. et al. (1992) Canine leukocyte cell adhesion molecules (LeuCAMs): characterization of the CD11/CD18 family. Tissue Antigens 40: 13-21, 2. Brodersen, R. et al. (1998) Analysis of the immunological cross reactivities of 213 well charaterized monoclonal antibodies with specificities against various leucocyte surface antigens of human and 11 animal species. Vet. Immunol. Immunopathol. 64: 1-13.

Additional Info

Recognizes canine CD11b cell surface antigen, a member of the alpha integrin family. Species Crossreactivity: goat, feline, mustelid, porcine, bovine and mink.

Alternative Names

Cell Surface Glycoprotein MAC1 Alpha Subunit, Complement Component Receptor 3 Alpha, CR3A, ITGAM, MAC1A, MO1A, Neutrophil Adherence Receptor

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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