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CD11b (Cell Surface Glycoprotein MAC1 Alpha Subunit, Complement Component Receptor 3 Alpha, CR3A, ITGAM, MAC1A, MO1A, Neutrophil Adherence Receptor) (FITC)

CD11b (Cell Surface Glycoprotein MAC1 Alpha Subunit, Complement Component Receptor 3 Alpha, CR3A, ITGAM, MAC1A, MO1A, Neutrophil Adherence Receptor) (FITC)

Cat no: C2262-36M

Supplier: United States Biological
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CD11b is also known as CD11b/CD18, Mac-1, alphaMbeta2 integrin, Cr3, MO-1, C3bi Receptor). CD11b is a marcophage-granulocyte specific antigen. Mac-1 macrophage differentiation antigen is associated with type three complement receptor and mediates adhesion to CD54 (ICAM-1). CD11b antigen is present on macrophages, granulocytes, natural killer cells, blood monocytes. CD11b is expressed on 8% spleen cells, 44% bone marrow cells and <1% of thymocytes. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 1:10; 10ul labels 10e6 cells in 100ul. Optimal dilutions to be determined by the researcher. Hybridoma: NS1 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
Catalogue number: C2262-36M
Reactivities: Bovine, Goat, Sheep
Hosts: Mouse
Applications: Flow Cytometry
Size: 100ug
Form: Supplied as a liquid in PBS, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
P type: Mab
Isotype: IgG2b
Purity: Purified by Protein G affinity chromatography.
Alternative names: Cell Surface Glycoprotein MAC1 Alpha Subunit, Complement Component Receptor 3 Alpha, CR3A, ITGAM, MAC1A, MO1A, Neutrophil Adherence Receptor
References: 1. Howard, C.J. and Naessens, J. (1993) Immunopathol. 39: 25-48, 2. Naessens, J. et al. (1993) Immunopathol. 39: 283-290. 3 Akesson, C.P. et al. (2008) Dev Comp Immunol. 32: 837-49. 4. Lecchi, C. et al. (2008) Vet Res. 39: 50. 5. Connelley, T. et al. (2011) Vet Res. 42: 37. 6. Kallapur, S.G. et al. (2011) Am J Physiol Lung Cell Mol Physiol. Jun 10. [Epub ahead of print] 7. Albenzio, M. and Caroprese, M. (2010) J. Dairy Research. 78: 43-48. 8. Graff, J.C. and Jutila, M.A. (2007) J Leukoc Biol. 82: 603-7. 9. Top, S. et al. (2011) J Virol. 85: 12982-94. 10. Albenzio, M. et al. (2012) J Dairy Sci. 95: 3877-87.
Additional info: Recognizes bovine CD11b cell surface antigen. Species Crossreactivity: goat and sheep

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