Home  >  Products  >  CD11B (Integrin alpha-M, CD11 Antigen-like Family Member B, CR-3 alpha Chain, Cell Surface Glycoprotein MAC-1 Subunit alpha, Leukocyte Adhesion Receptor MO1, Neutrophil Adherence Receptor, ITGAM, CR3A)
CD11B (Integrin alpha-M, CD11 Antigen-like Family Member B, CR-3 alpha Chain, Cell Surface Glycoprotein MAC-1 Subunit alpha, Leukocyte Adhesion Receptor MO1, Neutrophil Adherence Receptor, ITGAM, CR3A)

CD11B (Integrin alpha-M, CD11 Antigen-like Family Member B, CR-3 alpha Chain, Cell Surface Glycoprotein MAC-1 Subunit alpha, Leukocyte Adhesion Receptor MO1, Neutrophil Adherence Receptor, ITGAM, CR3A)

Cat no: C2262-39M

Supplier: United States Biological
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CD11b is a 170kD glycoprotein, also known as aM integrin, Mac-1 alpha subunit, Mol, CR3, or Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, NK cells, and some T and B cells. The M1/70 antibody can block CD11b-mediated cellular adhesion. This antibody is also cross-reactive with human CD11b. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)0.25ug/10e6 cells in 100ul volume Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2262-39M
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG2b,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Springer, T., et al., 1978. Eur. J. Immunol. 8:539. 2. Springer, T.A., et al., 1982. Immunol. Rev. 68:171. 3. Flotte, T.J., et al., 1983. Am. J. Pathol. 111:112. 4. Hata, H., et al., 2004. J. Clin. Invest. 114:582. 5. Zhang, Y., et al., 2002. J. Immunol. 168: 3088. 6. Olver, S., et al., 2006. Cancer Research 66:571. 7. Tan, S-L., et al., 2006. J. Immunol. 176:2872. 8. Ponomarev, E. D., et al., 2006. J. Immunol. 176:1402. 9. Dzhagalov, I., et al 2007. Blood 109:1620. 10. Fazilleau, N., et al., 2007. Nature Immunol. 8:753.
Additional info: Recognizes mouse CD11b.

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