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CD11B (L1) mAb

CD11B (L1) mAb

Cat no: MB8001

Supplier: Bioworld Technology, Inc.
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Integrin (alpha)M, also designated complement component receptor-3 (alpha), CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin (alpha)M combines with the Integrin (beta)2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin (alpha)M/(beta)2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
Catalogue number: MB8001
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P11215
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant Human CD11B (630aa-1104aa).
Species: CD11B (L1) mAb detects endogenous levels of CD11B protein.
Molecular weight: ~ 170 kDa
Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b; ITGAM; CD11B; CR3A; Integrin (alpha)M; CR-3(alpha); CR3(alpha)
Additional info: For research use only, not for use in diagnostic procedure.

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