CD137 (K107) Peptide

Cat no: BS2039P

Supplier: Bioworld Technology, Inc.

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CD137, also designated ILA and 4-1BB in mouse, belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. CD137 is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. Crosslinking of the CD137 ligand induces apoptosis in resting lymphocytes. In contrast, CD137 regulates peripheral monocyte survival by inducing a cytokine release profile, and is mediated by M-CSF and to a lesser extent by granulocyte-macrophage colony-stimulating factor and IL-3. Soluble forms of CD137 are found in sera from patients with rheumatoid arthritis and may provide a negative control mechanism for immune responses.

Catalogue number:	BS2039P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q07011
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide CD137 (K107). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA; CD137; TNFRSF9; CD137; ILA
Additional info:	This peptide can be used with studies using BS2039 CD137 (K107) pAb.

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CD137 (K107) Peptide

Cat no: BS2039P

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