CD1B Peptide

Cat no: BS60328P

Supplier: Bioworld Technology, Inc.

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The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with ?-2-Microglobulin and expressed on cortical thymocytes, Langerhans cells, a B cell subset and some dendritic cells. Specifically, CD1A is a marker for Langerhans cell histiocytosis (LCH) and is found on interdigitating cells. Adaptor-protein complexes and CD1-associated chaperones control CD1 trafficking, and the development and activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.

Catalogue number:	BS60328P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P29016
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide CD1B. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	T-cell surface glycoprotein CD1b; CD1b
Additional info:	This peptide can be used with studies using BS60328 CD1B pAb.

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CD1B Peptide

Cat no: BS60328P

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