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CD272 (W153) Peptide

Cat no: BS9212P

CD272 (W153) Peptide

B and T lymphocyte attenuator (BTLA,CD272) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are co-inhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecular switch that modulates T cell activation by propagating inhibitory signals through BTLA. The BTLA-HVEM interaction is conserved between mouse and human, suggesting that this system is an important pathway regulating lymphocyte activation.

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SPECIFICATIONS

Catalog Number

BS9212P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide CD272 (W153). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q7Z6A9

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS9212 CD272 (W153) pAb.

Alternative Names

BTLA; BTLA; BTLA1; CD272; CD272 antigen; FLJ16065; MGC129743;

SUPPLIER INFO

Bioworld Technology, Inc.

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