Home  >  Products  >  CD3 (Early T Cell Marker, T Cell receptor Complex, TCR)
CD3 (Early T Cell Marker, T Cell receptor Complex, TCR)

CD3 (Early T Cell Marker, T Cell receptor Complex, TCR)

Cat no: C2254-07K

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
CD3E is a 20kD chain of the CD3/T-cell receptor (TCR) complex which is composed of two CD3E, one CD3y, one CD3delta, one CD3Z (CD247), and a T-cell receptor (a/B or y/delta) heterodimer. It is found on all mature T lymphocytes, NK-T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation. This antibody is able to stimulate T cell activation. Applications: Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)0.25ug/10e5 cells in 100ul Immunohistochemistry: acetone-fixed, frozen Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2254-07K
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG2a,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Schlossman, S., et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York. 2. Knapp, W.1989. Leucocyte Typing IV. Oxford University Press, New York. 3. Barclay, N., et al. 1997. The Leucocyte Antigen Facts Book. Academic Press Inc. San Diego. 4. Sedelies, K. A., et al. 2004. J. Biol. Chem. 279:26581. 5. Rivollier, A., et al. 2004. Blood 104:4029. 6. Scharschmidt, E., et al. 2004. Mol. Cell Biol. 24:3860. 7. Smeltz, R. B., 2007. J. Immunol. 178:4786. 8. Sheng, W. et al.2007.ELSEVIER.580:6819. 8. Barclay, N., et al. 1993. The Leucocyte FactsBook. Academic Press. San Diego. 9. Beverly, P., et al. 1981. Eur. J. Immunol. 11:329. 10. Lanier, L., et al. 1986. J. Immunol. 137:2501-2507.
Additional info: Recognizes human CD3.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave