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CD4 (A429) Peptide

CD4 (A429) Peptide

Cat no: BS1617P

Supplier: Bioworld Technology, Inc.
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Cluster of Differentiation 4 (CD4) is a glycoprotein composed of an amino-terminal extracellular domain (four domains: D1-D4 with Ig-like structures), a transmembrane part and a short cytoplasmic tail. CD4 is expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages and dendritic cells, and plays an important role in the development and activation of T cells. On T cells, CD4 is the co-receptor for the T cell receptor (TCR), and these two distinct structures recognize the Antigen-Major Histocompatibility Complex (MHC). Specifically, the D1 domain of CD4 interacts with the beta2-domain of the MHC class II molecule. CD4 ensures specificity of the TCR-antigen interaction, prolongs the contact between the T cell and the antigen presenting cell and recruits the tyrosine kinase Lck, which is essential for T cell activation.
Catalogue number: BS1617P
Applications: Block/Neutralize/Inhibit
Swiss prot: P01730
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide CD4 (A429). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: CD4; CD4MUT
Additional info: This peptide can be used with studies using BS1617 CD4 (A429) pAb.

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