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CD4 (T-cell Surface Glycoprotein CD4, T-cell Surface Antigen T4/Leu-3, W3/25 Antigen) (PE)

Cat no: C2255-80C

CD4 (T-cell Surface Glycoprotein CD4, T-cell Surface Antigen T4/Leu-3, W3/25 Antigen) (PE)

CD4 is an ~55kD type I transmembrane glycoprotein that is expressed predominantly on thymocytes and the Th1, Th2, Th17, Tfh, and Treg subsets of mature T lymphocytes. In human, CD4 is additionally expressed on macrophages, neutrophils, monocytes, natural killer cells, and neurons and glial cells in the brain. CD4 binding to MHC class II molecules on presenting cells contributes to the formation of the immunological synapse. CD4 also functions as a chemotactic receptor for IL-16 and, in human, as a co-receptor for the gp120 surface glycoprotein of HIV-1.\n\nApplications:\nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nAbsorption: 488nm\n\nEmission: 565-605nm\n\nStorage and Stability:\nMay be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months at 4 degrees C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.

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SPECIFICATIONS

Catalog Number

C2255-80C

Size

100Tests

Applications

FC

Hosts

Mouse

Reactivities

Rat

Form

Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).

P Type

Mab

Purity

Purified by Protein A/G affinity chromatography.

Isotype

IgG2B

Additional Info

Recognizes rat CD4.

Read more on Supplier website

SUPPLIER INFO

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

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