Home  >  Products  >  CD45 (PTPRC, Protein Tyrosine Phosphatase, Receptor Type, C, B220, CD45, CD45 Antigen, CD45R, GP180, LCA, L-CA, Leukocyte Common Antigen Precursor, LY5, T200)

CD45 (PTPRC, Protein Tyrosine Phosphatase, Receptor Type, C, B220, CD45, CD45 Antigen, CD45R, GP180, LCA, L-CA, Leukocyte Common Antigen Precursor, LY5, T200)

Cat no: C2400-25A


Supplier: United States Biological
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CD45 is a transmembrane tyrosine phosphatase, expressed on nucleated hematopoitic cells, which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing. CD45 functions as a leukocyte membrane receptor signal transduction. It plays an essential role in the regulation of leukocyte activation, development, and function. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2400-25A
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 200ug
Form: Supplied as a liquid in PBS, pH 7.2.
P type: Mab
Isotype: IgG2a
Purity: Purified by Protein G affinity chromatography.
References: Mustelin, T. et al. (2004) Mol. Immunol. 41,687 ?" 700 ; Trowbridge, I.S. et. al. (1994) Annu. Rev. Immunol. 12,85 ?" 116 ; Justement, L.B. et. al. (1991) Science 252,1839 ?" 1842.
Additional info: Recognizes human CD45 (LCA)

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