CD59 (16.3A5, 1F5, CD59a, EJ16, EJ30, EL32, FLJ38134, FLJ92039, G344, 20kD Homologous Restriction Factor, HRF20, HRF-20, Ly-6-like Protein, Lymphocytic Antigen CD59/MEM43, MAC Inhibitory Protein, MAC-IP, MEM43 Antigen, Membrane Attack Complex (MAC) Inhibi

Applications: \nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nFlow Cytometry: 20ul labels human blood cells in 100ul whole blood.\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.

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SPECIFICATIONS

Catalog Number

C2413-22F

Size

100Tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.4, BSA, 15mM sodium azide. Labeled with fluorescein isothiocyanate (FITC).

P Type

Mab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG2a

References

1. Horejsi V. et al., Folia Biol. (Praha) 34, 12 (1986). (original description of MEM-43 antigen) Leucocyte Typing IV. Knapp W et al. (Eds.), Oxford University Press (1989). 2. Leucocyte Typing V. Schlossman S. et al. (Eds.), Oxford University Press (1995). 3. Forsberg U.H. et al., Immunogenetics 30, 188 (1989). 4. Cinek T. and Horejsi V., J. Immunol. 149, 2262 (1991). 5. Stefanova I. et al., Science 254, 1016 (1991). 6. Cebecauer M et al., Biochem. Biophys. Res. Commun. 234, 706 (1998). 7. Stefanova I. et al., Mol. Immunol. 26, 153 (1989).

Additional Info

Recognizes human CD59. Reacts with the well defined epitope (W40, R-53) on CD59.

Alternative Names

1F5 Antigen, 20kD Homologous Restriction Factor, CD59 Antigen, CD59 Antigen p18 20, CD59 Glycoprotein, CD59 Molecule, CD59 Molecule Complement Regulatory Protein, Human Leukocyte Antigen MIC11,