CD70 (D101) Peptide

The tumor necrosis factor (TNF) receptor family is composed of several type I integral membrane glycoproteins that exhibit homology in their cystine-rich extracellular domains. Members of this family include FAS, OX40, CD27 and CD30. Ligands for these receptors are often type II transmembrane glycoproteins, as is the case for CD27 and CD30. CD27 is a homodimeric lymphocyte-specific surface antigen present on T and B lymphocytes. Activation of the CD3 complex via the T cell receptor for antigen leads to an increase in CD27 expression. Together, CD27 and its ligand, CD70, generate co-stimulatory signals required for complete T cell activation. CD30 is a surface marker for neoplastic cells of the Hodgkin

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SPECIFICATIONS

Catalog Number

BS9259P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide CD70 (D101). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P32970

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS9259 CD70 (D101) pAb.

Alternative Names

CD 27L; CD 70; CD27 L; CD27 LG; CD27 ligand; CD27-L; CD27L; CD27LG; CD70; CD70 antigen; CD70 molecule; CD70; Ki 24 antigen; Ki24 antigen; Surface antigen CD70; TNFSF 7; TNFSF7;