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CD83 (P130) pAb

CD83 (P130) pAb

Cat no: BS2204

Supplier: Bioworld Technology, Inc.
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CD83 is a heavily glycosylated membrane protein of the immunoglobulin (Ig) superfamily that is expressed in mature dendritic cells, Langerhans cells and interdigitating reticulum cells within lymphoid tissues. Structurally, CD83 resembles other Ig superfamily members, which have an extracellular V-type Ig-like domain, a single transmembrane domain and a 40 residue cytoplasmic tail. CD83 expression is used as a marker for mature, antigen presenting dendritic cells that are capable of generating tumor-specific T cell immunity, a phenotype with implications as an anticancer vaccine. CD83-IgG1(fc) chimera studies indicate that CD83 is a sialic acid-binding, Ig-like lectin (Siglec) adhesion molecule that is involved in cell adhesion/signaling by hosting dendritic cell interactions with monocytes and CD8+ T cells..
Catalogue number: BS2204
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q01151
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 100-150 of Human CD83.
Species: CD83 (P130) pAb detects endogenous levels of CD83 protein.
Molecular weight: ~ 23, 45 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: CD83 antigen; hCD83; B-cell activation protein; Cell surface protein HB15; CD83
Additional info: For research use only, not for use in diagnostic procedure.

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