CD90 (THY1, Thy-1 Cell Surface Antigen, FLJ33325, Thy-1 T-cell antigen, Thy-1 Membrane Glycoprotein)

CD90 (CDw90, Thy-1) is the 25-35kD smallest member of the immunoglobulin gene superfamily. Human Thy-1 is highly glycosylated and is inserted into the cellular membrane via a glycosyl phosphatidylinositol anchor. The Thy-1 antigen has a broad tissue distribution. It is expressed in nervous tissue, connective tissue and various stomal cell lines. Thy-1 characterizes a rare (0.05 to 0.1%) subset of human fetal bone marrow cells, that contains multipotent hematopoietic progenitor activity. This antigen is expressed on 5 to 25% of CD34+ cells from human bone marrow, umbilical cord blood or fetal liver. CD34+ Thy-1+ cells include the most primitive hematopoietic progenitor cells measured in vitro including high proliferative potential colony-forming cells and cells capable of initiating long-term bone marrow culture.\n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:64,000\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C2441-65A

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Hum

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.

P Type

Pab

Purity

Purified by affinity chromatography.

Isotype

IgG

References

1. Saalbach A, Arnhold J, Lessig J, Simon JC, Anderegg U. Human Thy-1 induces secretion of matrix metalloproteinase-9 and CXCL8 from human neutrophils. Eur J Immunol. 2008 May;38(5):1391-403.

Additional Info

Recognizes human CD90/THY1. Sequence homology: canine, porcine.