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Cdc7 (F35) Peptide

Cat no: BS2447P

Cdc7 (F35) Peptide

DNA replication in eukaryotic cells is dependent on the phosphorylation of the pre-replicative complex (preRC) at the origin of replication. Two complexes of proteins mediate this event, the cyclin dependent kinase (CDK) complex, and the Cdc7 kinase-ASK complex. Human Cdc7 kinase consists of 574 amino acids with a molecular weight of 55 kDa. The activity of Cdc7 kinase oscillates during cell cycle. The major targets of Cdc7 kinase are proteins that belong to the MCM complex (mini chromosome maintenance proteins). Cdc7 kinase was also found to be important in meiosis, checkpoint responses, maintenance of chromosome structure, and repair.

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SPECIFICATIONS

Catalog Number

BS2447P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Cdc7 (F35). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

O00311

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2447 Cdc7 (F35) pAb.

Alternative Names

Cell division cycle 7-related protein kinase; CDC7-related kinase; HsCdc7; huCdc7; CDC7; CDC7L1

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