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CDK10 (E63) pAb

CDK10 (E63) pAb

Cat no: BS2312

Supplier: Bioworld Technology, Inc.
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Cdk10, also called PISSLRE, is a Cdc2-related kinase whose gene has been shown to encode two isoforms, each having a different function within the cell cycle. Although the two isoforms share nearly identical amino acid seqeunces, they differ at the C- and N- terminals. One Cdk isoform interacts with the transcription factor Ets-2, thereby modulating its transactivation activity, while the other is thought to have a role at the G2/M transition. Cdk10 mRNA has been shown to have the highest expression in lung, liver and kidney tissue, with gene upregulation implicated in cases of non-Hodgkin's follicular lymphoma.
Catalogue number: BS2312
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q15131
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 30-84 of Human Cdk10.
Species: Cdk10 (E63) pAb detects endogenous levels of Cdk10 protein.
Molecular weight: ~ 43 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Cyclin-dependent kinase 10; Cell division protein kinase 10; Serine/threonine-protein kinase PISSLRE; CDK10
Additional info: For research use only, not for use in diagnostic procedure.

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