CDK5RAP2 (CDK5RAP2, CEP215, KIAA1633, CDK5 regulatory subunit-associated protein 2, CDK5 activator-binding protein C48, Centrosome-associated protein 215)

Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein may also be a substrate of neuronal CDC2-like kinase. Multiple transcript variants exist for this gene, but the full-length nature of only two has been determined.\n\nApplications:\nSuitable for use in Western Blot, ELISA.\n\nRecommended Dilution: \nELISA: 1:1,000\nWestern Blot: 1:500~2000\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

030869

Size

100ul

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid, crude ascites with 0.09% sodium azide.

P Type

Mab

Purity

Ascites

Isotype

IgM

References

Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010) \nWang, Z., et al. J. Biol. Chem. 285(29):22658-22665(2010) \nJoslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010) \nLee, S., et al. Cell Cycle 9(4):774-783(2010) \nBarber, M.J., et al. PLoS ONE 5 (3), E9763 (2010)

Additional Info

Human

Alternative Names

CDK5RAP2, CEP215, KIAA1633, CDK5 regulatory subunit-associated protein 2, CDK5 activator-binding protein C48, Centrosome-associated protein 215