CFI Peptide

Cat no: BS5716P

Supplier: Bioworld Technology, Inc.

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Additional Information

The complement pathway is an important host defense system that contributes to both innate and acquired immunity. There are three pathways of complement activation: the classical pathway, lectin pathway and alternative pathway. Complement protein Factor I is a key serine protease that modulates the complement cascade by regulating the levels of C3 convertases. It circulates in plasma as a heavily N-glycosylated heterodimer made up of two disulfide linked chains, each carrying three N-linked oligosaccharide chains that may have both structural and functional roles in the interactions with the natural substrate and the cofactor during catalysis. Factor I is a serine protease with a high degree of specificity for C3b and C4b. It requires protein cofactors for cleavage of these complement proteins; Factor H, CR1 or MCP are required for C3b cleavage, and C4bp or CR1 are required for C4b cleavage.

Catalogue number:	BS5716P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P05156
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide CFI. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Complement factor I; C3B/C4B inactivator; Complement factor I heavy chain; IF
Additional info:	This peptide can be used with studies using BS5716 CFI pAb.

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CFI Peptide

Cat no: BS5716P

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