Home  >  Products  >  CFP10 (mtsA10, 10kD culture filtrate antigen cfp10, Culture filtrate protein 10, ESAT6 like protein esxB, esxB, lhp, Secreted antigenic protein MTSA 10 )

CFP10 (mtsA10, 10kD culture filtrate antigen cfp10, Culture filtrate protein 10, ESAT6 like protein esxB, esxB, lhp, Secreted antigenic protein MTSA 10 )

Cat no: C3199-01B


Supplier: United States Biological
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CFP10 (10kD culture filtrate protein) is a low molecular weight protein isolated from Mycobacterium tuberculosis culture filtrates. CFP10 and the 6kD early secretory antigen of T cells (ESAT6) are secreted in abundance by Mycobacterium tuberculosis and are frequently recognized by T cells from infected people. The genes encoding these proteins have been deleted from the genome of the vaccine strain Bacille Calmette Guerin (BCG). CFP10 is one of a small number of secreted M. tuberculosis proteins now identified, that appear to play key roles in tuberculosis pathogenesis and in the stimulation of immunity. This antibody was raised by a genetic immunization technique. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.2-1ug/ml under reducing conditions. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C3199-01B
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein A affinity chromatography. >95% by SDS-PAGE.
Alternative names: mtsA10, 10kD culture filtrate antigen cfp10, Culture filtrate protein 10, ESAT 6 like protein esxB, esxB, lhp, Secreted antigenic protein MTSA 10
Additional info: Recognizes CFP10 (LHP), a 12,3kD antigen encoded by gene Rv3874 of Mycobacterium tuberculosis. The antibody recognizes CFP10 of Mycobacterium tuberculosis H37Rv and Mycobacterium bovis; it reacts also with recombinant antigen produced in Escherichia coli.

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