CGA pAb

Gonadotropin (also designated choriogonadotropin) is a hormone produced by the placenta in the first trimester of pregnancy and exists as a heterodimer formed from a common (alpha) chain and a unique (beta) chain. The unique (beta) chain confers biological specificity to thyrotropin, Lutropin, follitropin and gonadotropin. The secreted (alpha) subunit maps to human chromosome 6 and the (beta) subunit maps to human chromosome 19. Gonadotropin stimulates the ovaries to produce and maintain normal levels of the steroids essential for maintaining pregnancy, including estrogen and progesterone. Gonadotropin is a member of the cystine knot growth-factor superfamily, a group of proteins that contain a distinct arrangement of six cysteine residues and are expressed in placenta. The proper secretion and dimerization of gonadotropin depends on the conformation of the cystine knot, although biological activity is independent of this conformation.\n

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SPECIFICATIONS

Catalog Number

BS6281

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human CGA.

Species

CGA pAb detects endogenous levels of CGA protein.

Dilutions

WB: 1:500~1:2000\nIHC: 1:50~1:200

Swiss Prot

P01215

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 13 kDa

Alternative Names

Anterior pituitary glycoprotein hormones common subunit alpha; CG alpha; CG-alpha; CGA; Choriogonadotropin Alpha Chain; Chorionic Gonadotrophin Alpha Subunit; Chorionic gonadotrophin subunit alpha; Chorionic gonadotropin alpha polypeptide; Follicle Stimulating Hormone Alpha Chain; Follicle-stimulating hormone alpha chain; Follitropin Alpha Chain; FSH Alpha; FSH-alpha; FSHA; GLHA; Glycoprotein hormones alpha chain; Glycoprotein Hormones Alpha Polypeptide; GPH Alpha; GPHa; GPHA1; HCG; LHA; L