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cGKII (D412) Peptide

cGKII (D412) Peptide

Cat no: BS2483P

Supplier: Bioworld Technology, Inc.
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cGKII (cGMP-dependent protein kinase type II) is a major receptor of intracellular cGMP, and mediates a plethora of physiological responses. cGKII has a predicted molecular weight of 86 kDa, and contains a conserved leucine zipper motif at the amino terminus. It is expressed in small intestine, colon, prostate, and human brain tissues, and the cGKII gene maps to chromosome 4q13.1-q21.1. cGKII has been shown to regulate the ion transport system in the intestine. Myristoylation of the penultimate glycine in cGKII appears to be essential for directing cGKII to the membrane, since cGKII is devoid of any hydrophobic transmembrane domains. The translocation of cGKII from the cytosol to the membrane allows it to function properly in regulating intestinal ion transport.
Catalogue number: BS2483P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q13237
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide cGKII (D412). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: cGMP-dependent protein kinase 2; cGK 2; cGK2; cGMP-dependent protein kinase II; cGKII; PRKG2; PRKGR2
Additional info: This peptide can be used with studies using BS2483 cGKII (D412) pAb.

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