Home  >  Products  >  Channel Kinase 1 (CHAK1, EC 2.7.11.1, FLJ20117, FLJ25718, LTRPC7, TRP-PLIK, TRPM7)
Channel Kinase 1 (CHAK1, EC 2.7.11.1, FLJ20117, FLJ25718, LTRPC7, TRP-PLIK, TRPM7)

Channel Kinase 1 (CHAK1, EC 2.7.11.1, FLJ20117, FLJ25718, LTRPC7, TRP-PLIK, TRPM7)

Cat no: C3445-26

Supplier: United States Biological
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The TRPM7 (Transient Receptor Protein-PhosphoLipase C-Interacting Kinase) protein is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. TRPM7, however, is unique among the TRP channel proteins because it is bi-functional. It not only controls ion channels but it also acts as a kinase, phosphorylating proteins. Positive Control: Daudi lysate Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 2-4ug/ml. A 160-170kD band is seen in Daudi cell lysate. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C3445-26
Reactivities: Human
Hosts: Goat
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in TBS, pH 7.2, containing 0.5% BSA and 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: CHAK, Homolog of mouse transient receptor potential-phospholipase C-interacting kinase, LTRPC ion channel family member 7, Transient receptor potential cation channel subfamily M member 7
References: Nadler MJ et al. LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability. Nature 411:590-5 (2001).
Additional info: Species Crossreactivity: Crossreacts with Human. Expected to crossreact with Rat due to sequence homology.

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