Home  >  Products  >  Channel Kinase 1 (CHAK1, EC 2.7.11.1, FLJ20117, FLJ25718, LTRPC7, TRP-PLIK, TRPM7)
Channel Kinase 1 (CHAK1, EC 2.7.11.1, FLJ20117, FLJ25718, LTRPC7, TRP-PLIK, TRPM7)

Channel Kinase 1 (CHAK1, EC 2.7.11.1, FLJ20117, FLJ25718, LTRPC7, TRP-PLIK, TRPM7)

Cat no: C3445-26A

Supplier: United States Biological
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The TRPM7 (Transient Receptor Protein-PhosphoLipase C-Interacting Kinase) protein is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. TRPM7, however, is unique among the TRP channel proteins because it is bi-functional. It not only controls ion channels but it also acts as a kinase, phosphorylating proteins. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C3445-26A
Reactivities: Human, Rat
Hosts: Rabbit
Applications: Immunoprecipitation, Western Blot
Size: 100ul
Form: As reported
P type: Pab
Purity: Serum
Alternative names: CHAK, Homolog of mouse transient receptor potential-phospholipase C-interacting kinase, LTRPC ion channel family member 7, Transient receptor potential cation channel subfamily M member 7
References: 1. Runnels, L., et al. Sciencexpress, 18 January, 2001. 2. Harteneck, C. TINS, 23(4): 159-166. 2000.
Additional info: Specific for TRPM7. Recognizes overexpressed human TRPM7. It does not appear to recognize overexpressed mouse TRPM7. It does not work on endogenous samples tested for western analysis (human, rat and mouse cell lines). Other species have not been tested.

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