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CHD3 (C-terminus) mAb

CHD3 (C-terminus) mAb

Cat no: MB0061


Supplier: Bioworld Technology, Inc.
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This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Catalogue number: MB0061
Reactivities: Human
Hosts: Mouse
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q12873
Dilutions: WB: 1:1000 IHC: 1:500 FC: 1:50~100
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to the C-terminus of Human CHD3.
Species: This antibody detects endogenous levels of CHD3 (C-terminus) and does not cross-react with related proteins
Molecular weight: Predicted band size:226KDa Observed band size:260KDa
Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Chromodomain-helicase-DNA-binding protein 3; CHD-3; Hzfh; Zinc finger helicase; Mi2-alpha; ATP-dependent helicase CHD3
Additional info: For research use only, not for use in diagnostic procedure.

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