Home  >  Products  >  Chloride Intracellular Channel 1 (CLIC 1, CLIC1, Chloride Channel ABP, G6, hRNCC, Nuclear Chloride Ion Channel 27, NCC27, p64CLCP, Regulatory Nuclear Chloride Ion Channel Protein, RNCC Protein)

Chloride Intracellular Channel 1 (CLIC 1, CLIC1, Chloride Channel ABP, G6, hRNCC, Nuclear Chloride Ion Channel 27, NCC27, p64CLCP, Regulatory Nuclear Chloride Ion Channel Protein, RNCC Protein)

Cat no: C4363-10C


Supplier: United States Biological
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Chloride intracellular channel protein 1 (CLIC1) is a part of the CLIC family of proteins. This family of proteins reconstitute in phospholipid vesicles and have been shown to have chloride channel action. CLIC1 may rotate between membrane-bound and soluble forms since it has been seen as a membrane protein and in the cytoplasm. When there is a lack of detergent, CLIC1 becomes membrane-bound and can act as an anion-selective channel. Recently, it has been shown that CLIC1 is required in angiogenesis and has a part in controlling integrin cell surface expression. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Western Blot: 0.25ug/ml detects CLIC1 on 10ug of human liver tissue lysate. Optimal dilutions to be determined by the researcher. Positive Control: Human liver tissue lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C4363-10C
Reactivities: Human
Hosts: Mouse
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
P type: Mab
Isotype: IgG2a,k
Purity: Purified by Protein G affinity chromatography.
Alternative names: chloride intracellular channel , Chloride channel ABP, RNCC protein, Nuclear chloride ion channel 27, nuclear chloride ion channel protein, Regulatory nuclear chloride ion channel protein, chloride intracellular channel protein 1
Additional info: Recognizes human CLIC1.

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