Cholecystokinin A Receptor (CCKA Receptor, CCKAR, AW106902)

Cat no: C5042-20H

Supplier: United States Biological

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Additional Information

Cholecystokinin A Receptor (CCKAR) is one of two 7TM receptors for cholecystokinin peptide hormones. This GPCR is involved in gallbladder contraction, insulin secretion, and central nervous system function. CCK-A R has been implicated in pancreatic tumorigenesis as well as the pathogenesis of eating disorders and drug addiction. Human CCK-A R shares 89% aa sequence identity with mouse and rat CCKAR. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:64,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	C5042-20H
Reactivities:	Rat
Hosts:	Goat
Applications:	Western Blot
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type:	Pab
Isotype:	IgG
Purity:	Purified by affinity chromatography.
References:	1. Bi S, Scott KA, Kopin AS, Moran TH. Differential roles for cholecystokinin a receptors in energy balance in rats and mice. Endocrinology. 2004 Aug;145(8):3873-80. Epub 2004 May 3. PMID: 15123537
Additional info:	Recognizes rat CCKA. Sequence Homology: mouse, rabbit.

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Cholecystokinin A Receptor (CCKA Receptor, CCKAR, AW106902)

Cat no: C5042-20H

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