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Choriogonadotropin Subunit beta (hCG, CG-beta, Chorionic Gonadotrophin Chain beta, CGB, CGB3)

Choriogonadotropin Subunit beta (hCG, CG-beta, Chorionic Gonadotrophin Chain beta, CGB, CGB3)

Cat no: C5069-70F

Supplier: United States Biological
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Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the a-and b-subunits. The a-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C5069-70F
Reactivities: Human
Hosts: Goat
Applications: ELISA
Size: 1mg
Form: Supplied as a liquid in 0.1M potassium phosphate buffer, pH 7.8, 0.85% sodium chloride, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes alpha subunit and beta subunit of the whole hCG molecule.

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