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CHRDL1 mAb

CHRDL1 mAb

Cat no: MB0127


Supplier: Bioworld Technology, Inc.
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This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described. Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embyonic bone formation By similarity. May also play an important role in regulating retinal angiogenesis trough modulation of BMP4 actions in endothelial cells.
Catalogue number: MB0127
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q9BU40
Dilutions: WB: 1:1000 ICC: 1:300
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human CHRDL1.
Species: CHRDL1 mAb detects endogenous levels of CHRDL1 protein.
Molecular weight: Predicted band size:57kDa Observed band size:57kDa
Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Neuralin-1 Neurogenesin-1 Ventroptin; CHL; VOPT; NRLN1; dA141H5.1
Additional info: For research use only, not for use in diagnostic procedure.

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